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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
Drug Name
Drug ID
ATC Code
DrugBank ID
KEGG ID
PubChem ID
CAS RN
Molecular Formula
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ADR Ontology
ADR Term
Respiratory depression
ADR ID
BADD_A03808
ADR Hierarchy
17
Nervous system disorders
17.02
Neurological disorders NEC
17.02.05
Neurological signs and symptoms NEC
17.02.05.047
Respiratory depression
22
Respiratory, thoracic and mediastinal disorders
22.02
Respiratory disorders NEC
22.02.01
Breathing abnormalities
22.02.01.010
Respiratory depression
Description
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code
10038678
MeSH ID
D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Depression respiratory | Respiration depressed | Respiratory depression | Respiratory depression postoper | Central respiratory depression | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Not Available
Not Available
Not Available
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00504
Clopidogrel
-
-
BADD_D00511
Clozapine
-
-
BADD_D00516
Codeine
0.003828%
BADD_D00517
Codeine sulfate
-
-
BADD_D00545
Cyclobenzaprine
0.000051%
BADD_D00564
Dabigatran etexilate
-
-
BADD_D00577
Dantrolene sodium
-
-
BADD_D00581
Daptomycin
0.000213%
BADD_D00611
Desflurane
-
-
BADD_D00629
Dexmedetomidine
0.002408%
BADD_D00630
Dexmedetomidine hydrochloride
-
-
BADD_D00636
Dextroamphetamine
0.001737%
BADD_D00638
Dextromethorphan
-
-
BADD_D00648
Diazepam
0.004802%
BADD_D00653
Diclofenac
0.000178%
BADD_D00655
Diclofenac potassium
-
-
BADD_D00656
Diclofenac sodium
-
-
BADD_D00668
Digoxin
0.000111%
BADD_D00670
Dihydrocodeine
-
-
BADD_D00686
Diphenhydramine
0.001120%
BADD_D00720
Doxepin
0.003625%
BADD_D00770
Enflurane
-
-
BADD_D00773
Entacapone
0.012575%
BADD_D00809
Escitalopram
-
-
BADD_D00850
Etodolac
-
-
BADD_D00871
Felbamate
-
-
BADD_D00879
Fentanyl
0.023228%
BADD_D00880
Fentanyl citrate
-
-
BADD_D00932
Fluoxetine
0.000272%
BADD_D00941
Flurbiprofen
-
-
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